"Fallout 4" is out today. I don't want to spoil anything, but it has significantly more Lovecraftian content than 3 and much of it is located exactly where Mythos fans would expect. I really hope the rumors that at least one of the DLC packages is heavily Lovecraft-influenced are true.
Update: And the Dunwich Building saga from 3 continues. This is a genuinely disturbing location.